More on Speckled Lentiginous Nevus Syndrome

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Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi.

BACKGROUND Currently, there is disagreement as to whether speckled lentiginous nevi (nevi spili) are congenital or acquired pigmented lesions. Part of this controversy is related to the natural history of these lesions that often present at birth as hyperpigmented patches and then take several years to reach their more readily recognized spotted form. Arguments in favor of speckled lentiginous ...

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Segmental Speckled Lentiginous Nevus Exacerbated by Pregnancy in an Otherwise Healthy Female: A Case Report

Speckled lentiginous nevi (SLN), or nevus spili, are seen in 0.2% to 2.3% of the population, presenting as tan patches with overlying hyperpigmented macules or papules in a speckled arrangement. Segmental SLN represent a small subset of SLN, with the segmental type comprised of larger, unilateral lesions that may rarely give rise to melanomas and have been reported to proliferate in response to...

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Giant Maculo-Papular Speckled Lentiginous Nevus Associated with Isolated and Centrofacial Located Lentiginosus

Lentigines are usually flat, pigmented macules on the skin and mucosa. These lesions are characterized by mostly smaller than 0.5 cm, irregular borders and different shades of brown and black. They can be in the form of circumscribed or widespread lesions, and occur either as isolated lesion or as a part of some congenital syndromes. The speckled lentiginous nevus is also named as Nevus Spilus ...

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Phacomatosis pigmentokeratotica or the Schimmelpenning‐Feuerstein‐Mims syndrome?

Cutaneous symptoms in some patients with clinical picture of Schimmelpenning-Feuerstein-Mims syndrome can include a speckled lentiginous nevus, also known as nevus spilus. Recent investigations show that somatic heterozygous HRAS mutations are present in the sebaceous and speckled lentiginous nevus tissues of patients with combination of two nevi.

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Phacomatosis Pigmentokeratotica without Extracutaneous Abnormalities: A Case Study Involving a Preterm Baby

Phacomatosis pigmentokeratotica (PPK) is a rare syndrome defined by the association of an organoid nevus occasionally with sebaceous differentiation, a speckled lentiginous nevus, and other extracutaneous anomalies. A preterm male infant of only 830 g at 27 week gestational age had an organoid nevus showing sebaceous differentiation. Also, he had multiple speckled-lentiginous nevus. Correlating...

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ژورنال

عنوان ژورنال: Dermatology

سال: 2010

ISSN: 1421-9832,1018-8665

DOI: 10.1159/000321473